Ngakhale kuti sitingazindikire, aliyense padziko lapansi angakhudzidwe ndi kugwiritsa ntchito mankhwala osabala. Izi zitha kuphatikiza kugwiritsa ntchito singano kubaya katemera, kugwiritsa ntchito mankhwala opulumutsa moyo monga insulin kapena epinephrine, kapena mu 2020 mwachiyembekezo kuti ndizosowa koma zenizeni, kuyika chubu chothandizira kuti odwala omwe ali ndi Covid-19 apume.
Mankhwala ambiri olera kapena osabala amatha kupangidwa pamalo aukhondo koma osabereka kenako amafafanizidwa, koma palinso mankhwala ena ambiri osabala omwe sangafafanizidwe.
Ntchito zodziwika bwino zopha tizilombo toyambitsa matenda zingaphatikizepo kutentha kwachinyezi (ie, autoclaving), kutentha kouma (ie, depyrogenation oven), kugwiritsa ntchito mpweya wa hydrogen peroxide, ndi kugwiritsa ntchito mankhwala ochita pamwamba omwe amatchedwa ma surfactants (monga 70% isopropanol [ IPA] kapena sodium hypochlorite [bleach]), kapena gamma walitsa pogwiritsa ntchito cobalt 60 isotope.
Nthawi zina, kugwiritsa ntchito njirazi kungayambitse kuwonongeka, kuwonongeka kapena kutsekedwa kwa chinthu chomaliza. Mtengo wa njirazi udzakhudzanso kwambiri kusankha njira yolera yotseketsa, chifukwa wopanga ayenera kuganizira momwe izi zimakhudzira mtengo wa mankhwala omaliza. Mwachitsanzo, wopikisana naye akhoza kufooketsa mtengo wamtengo wapatali, kotero kuti akhoza kugulitsidwa pamtengo wotsika. Izi sizikutanthauza kuti ukadaulo woletsa kubereka sungagwiritsidwe ntchito komwe kuseptic processing umagwiritsidwa ntchito, koma udzabweretsa zovuta zatsopano.
Vuto loyamba la aseptic processing ndi malo omwe mankhwalawa amapangidwira. Malowa ayenera kumangidwa m'njira yochepetsera malo otsekeredwa, kugwiritsa ntchito zosefera zamagetsi zamagetsi (zotchedwa HEPA) kuti zizitha mpweya wabwino, komanso zosavuta kuyeretsa, kusamalira, ndi kuwononga.
Chovuta chachiwiri ndi chakuti zipangizo zomwe zimagwiritsidwa ntchito popanga zigawo, zapakati, kapena zomaliza m'chipindamo ziyeneranso kukhala zosavuta kuyeretsa, kusungirako, komanso kusagwa (kutulutsa tinthu tating'onoting'ono pokhudzana ndi zinthu kapena mpweya). M'makampani omwe akuwongolera nthawi zonse, popanga zatsopano, kaya muyenera kugula zida zaposachedwa kapena kumamatira matekinoloje akale omwe atsimikizira kuti ndi othandiza, padzakhala ndalama zopindulitsa. Zida zikamakalamba, zimatha kuwonongeka, kulephera, kutayikira kwamafuta, kapena kumeta ubweya wina (ngakhale pamlingo wocheperako), zomwe zitha kuwononga malowo. Ichi ndichifukwa chake dongosolo lokonzekera nthawi zonse ndi lovomerezeka ndilofunika kwambiri, chifukwa ngati zidazo zitayikidwa ndikusamalidwa bwino, mavutowa amatha kuchepetsedwa komanso kuwongolera mosavuta.
Kenako kukhazikitsidwa kwa zida zenizeni (monga zida zokonzera kapena kutulutsa zida ndi zinthu zomwe zimafunikira kupanga chomaliza) kumabweretsa zovuta zina. Zinthu zonsezi ziyenera kuchotsedwa pamalo otseguka komanso osayendetsedwa bwino kupita kumalo opangira aseptic, monga galimoto yobweretsera, malo osungiramo zinthu, kapena malo opangirako. Pazifukwa izi, zinthuzo ziyenera kuyeretsedwa musanalowe m'malo opangira aseptic, ndipo gawo lakunja lazovala liyenera kutsukidwa musanalowe.
Momwemonso, njira zochotsera kachilomboka zimatha kuwononga zinthu zomwe zimalowa m'malo opangira aseptic kapena zitha kukhala zokwera mtengo kwambiri. Zitsanzo za izi zingaphatikizepo kutentha kwa kutentha kwa mankhwala omwe akugwira ntchito, omwe amatha kupanga mapuloteni kapena ma molecular bond, potero atseketsa pawiri. Kugwiritsa ntchito ma radiation ndikokwera mtengo kwambiri chifukwa kusungunula kutentha kwachinyontho ndi njira yachangu komanso yotsika mtengo pazinthu zopanda porous.
Kuchita bwino ndi kulimba kwa njira iliyonse kuyenera kuwunikidwanso nthawi ndi nthawi, yomwe nthawi zambiri imatchedwa revalidation.
Vuto lalikulu ndilakuti ntchito yokonza idzakhudza kuyanjana pakati pa anthu panthawi ina. Izi zikhoza kuchepetsedwa pogwiritsa ntchito zotchinga monga glove pakamwa kapena pogwiritsa ntchito makina, koma ngakhale ndondomekoyi ikufuna kuti ikhale yokhayokha, zolakwika kapena zolakwika zilizonse zimafuna kulowererapo kwa anthu.
Thupi la munthu nthawi zambiri limanyamula mabakiteriya ambiri. Malinga ndi malipoti, munthu wamba amapangidwa ndi 1-3% ya mabakiteriya. Ndipotu chiwerengero cha mabakiteriya ndi chiwerengero cha maselo aumunthu ndi pafupifupi 10: 1.1
Popeza mabakiteriya amapezeka paliponse m'thupi la munthu, n'zosatheka kuwathetsa. Thupi likamasuntha, limangotaya khungu lake, chifukwa cha kuwonongeka ndi kung'ambika komanso kutuluka kwa mpweya. M'moyo wonse, izi zimatha kufika pafupifupi 35 kg. 2
Khungu lonse lokhetsedwa ndi mabakiteriya adzakhala pachiwopsezo chachikulu cha kuipitsidwa panthawi ya aseptic, ndipo ayenera kuwongoleredwa ndikuchepetsa kuyanjana ndi njirayo, komanso kugwiritsa ntchito zotchinga ndi zovala zosakhetsa kuti muteteze chitetezo. Mpaka pano, thupi la munthu palokha ndi chinthu chofooka kwambiri mu unyolo woletsa kuwononga chilengedwe. Chifukwa chake, ndikofunikira kuchepetsa kuchuluka kwa anthu omwe akutenga nawo gawo pazochita za aseptic ndikuwunika momwe chilengedwe chimayipitsira tizilombo tomwe timapanga. Kuphatikiza pa njira zoyeretsera bwino komanso zophera tizilombo toyambitsa matenda, izi zimathandiza kuti bioburden ya malo opangira aseptic ikhale yotsika kwambiri ndipo imalola kulowererapo koyambirira pakakhala "nsonga" zilizonse zoipitsa.
Mwachidule, ngati n'kotheka, njira zambiri zomwe zingatheke zitha kuchitidwa kuti muchepetse kuipitsidwa komwe kumalowa mu njira ya aseptic. Zochita izi zikuphatikiza kuwongolera ndi kuyang'anira chilengedwe, kukonza zida ndi makina ogwiritsidwa ntchito, kutsekereza zida zolowera, ndikupereka chitsogozo cholondola panjirayo. Palinso njira zina zambiri zowongolera, kuphatikiza kugwiritsa ntchito kukakamiza kosiyana kuchotsa mpweya, tinthu tating'onoting'ono, ndi mabakiteriya pamalo opangira. Osatchulidwa apa, koma kuyanjana kwa anthu kudzatsogolera ku vuto lalikulu la kulephera kuwononga kuwononga. Choncho, ziribe kanthu kuti ndi njira yotani yomwe ikugwiritsidwa ntchito, kuyang'anitsitsa kosalekeza ndi kuwunika kosalekeza kwa njira zoyendetsera ntchito zomwe zimagwiritsidwa ntchito nthawi zonse zimafunika kuti odwala omwe akudwala kwambiri apitirizebe kupeza njira zotetezeka komanso zoyendetsedwa bwino zopangira aseptic.